The intramolecular photocycloaddition of chalcones to give cyclobutanes has proven to be a fast and simple method to shrink a cyclophane ring to a tricyclic system, in order to prepare potential ditopic receptors. In particular, the chalcone 1, having dioxyethylene chains as spacers, is converted in high yield to the cyclobutane 2. NOESY spectroscopy indicates that the formation of 2 occurs by a head-to-head syn ring closure. (C) 2003 Elsevier Science Ltd. All rights reserved.
Synthesis of a ditopic cyclophane based on the cyclobutane ring by chalcone photocycloaddition / Francesca R., Cibin; Doddi, Giancarlo; Mencarelli, Paolo. - In: TETRAHEDRON. - ISSN 0040-4020. - STAMPA. - 59:19(2003), pp. 3455-3459. [10.1016/s0040-4020(03)00475-7]
Synthesis of a ditopic cyclophane based on the cyclobutane ring by chalcone photocycloaddition
DODDI, Giancarlo;MENCARELLI, Paolo
2003
Abstract
The intramolecular photocycloaddition of chalcones to give cyclobutanes has proven to be a fast and simple method to shrink a cyclophane ring to a tricyclic system, in order to prepare potential ditopic receptors. In particular, the chalcone 1, having dioxyethylene chains as spacers, is converted in high yield to the cyclobutane 2. NOESY spectroscopy indicates that the formation of 2 occurs by a head-to-head syn ring closure. (C) 2003 Elsevier Science Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.