Background. We aimed to determine if strain rate (SR) imaging (ApliQ, Toshiba corp.) during low-dose dobutamine echocardiography (LDDE) provide valuable informations in detecting hibernating but viable myocardium. Methods. LDDE (10 mcg/Kg/min) was performed in 19 pts (age 5813 years) with chronic ischemic left ventricular dysfunction (LVEF 2810%) within 30 days before myocardial revascularization (PTCA 10 pts, CABG 9 pts). Viability by LDDE-2D was defined as an improvement in contractility of 1 grade. Peak strain rate and tissue Doppler were measured at the base, mid and apex in the apical 4 and 2 chamber views (septum, lateral, anterior, inferior). Peak early diastolic (E-SR) and late diastolic (A-SR) myocardial SR was determined at baseline and during dobutamine infusion. Viability by LDDE-SR was defined as an increase in peak SR >15% compared to baseline in > 2 contiguous segments. Results. Mean increase in heart rate during stress tests was 17 +/- 3 beats/min for LDDE-2D and 15 +/- 6 beats/min for LDDE-SR (p=NS). Follow-up echocardiography at rest was repeated 60 days after coronary revascularization. In 97 akinetic segments, contractile reserve was detected in 44 (45%) by LDDE-2D and 54 (56%) by LDDE-SR. At following echocardiography, functional improvement of wall thickening was identified in 57 (59%) segments. The sensitivity and specificity for predicting functional recovery were 87% and 92% for LDDE-2D and 94% and 97% for LDDE-SR. Conclusions. LDDE-SR appears as feasibile as LDDE-DE in predicting recovery of regional ventricular function after coronary revascularization but with the advantage of being automated and quantitative.
Assessement of viability by strain rate imaging in ischemic cardiomiopathy / Vitarelli, Antonino; Conde, Y; Ciminio, E; D'Angeli, Ilaria; Ciciarello, Francesco Luigi; D'Orazio, Simona; Stellato, Simona; Padella, V.. - In: CORONARY ARTERY DISEASE. - ISSN 0954-6928. - STAMPA. - 5:(2003), p. 1270. (Intervento presentato al convegno 5th International Congress on Coronary Artery Disease tenutosi a Florence, Italy, nel Oct 2003).
Assessement of viability by strain rate imaging in ischemic cardiomiopathy.
VITARELLI, Antonino;D'ANGELI, ILARIA;CICIARELLO, Francesco Luigi;D'ORAZIO, SIMONA;STELLATO, SIMONA;
2003
Abstract
Background. We aimed to determine if strain rate (SR) imaging (ApliQ, Toshiba corp.) during low-dose dobutamine echocardiography (LDDE) provide valuable informations in detecting hibernating but viable myocardium. Methods. LDDE (10 mcg/Kg/min) was performed in 19 pts (age 5813 years) with chronic ischemic left ventricular dysfunction (LVEF 2810%) within 30 days before myocardial revascularization (PTCA 10 pts, CABG 9 pts). Viability by LDDE-2D was defined as an improvement in contractility of 1 grade. Peak strain rate and tissue Doppler were measured at the base, mid and apex in the apical 4 and 2 chamber views (septum, lateral, anterior, inferior). Peak early diastolic (E-SR) and late diastolic (A-SR) myocardial SR was determined at baseline and during dobutamine infusion. Viability by LDDE-SR was defined as an increase in peak SR >15% compared to baseline in > 2 contiguous segments. Results. Mean increase in heart rate during stress tests was 17 +/- 3 beats/min for LDDE-2D and 15 +/- 6 beats/min for LDDE-SR (p=NS). Follow-up echocardiography at rest was repeated 60 days after coronary revascularization. In 97 akinetic segments, contractile reserve was detected in 44 (45%) by LDDE-2D and 54 (56%) by LDDE-SR. At following echocardiography, functional improvement of wall thickening was identified in 57 (59%) segments. The sensitivity and specificity for predicting functional recovery were 87% and 92% for LDDE-2D and 94% and 97% for LDDE-SR. Conclusions. LDDE-SR appears as feasibile as LDDE-DE in predicting recovery of regional ventricular function after coronary revascularization but with the advantage of being automated and quantitative.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
