Highly functionalised aziridines are readily obtained in high yields (up to 95%) under mild conditions from the reaction of trisubstituted olefins bearing different groups with nosyloxycarbamates in the presence of calcium oxide. We propose a possible explanation for the different reactivities observed between these olefins and the aminating agents. Reagent-controlled stereoselective amination reactions led to the expected products with high conversions and purities.
Aza-MIRC Reactions of Sulfonyl-Activated Hydroxycarbamates with alfa,beta-Difunctionalised Acrylates / Fioravanti, Stefania; Morreale, Alberto; Pellacani, Lucio; Tardella, Paolo Antonio. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - STAMPA. - -:(2003), pp. 4549-4552. [10.1002/ejoc.200300425]
Aza-MIRC Reactions of Sulfonyl-Activated Hydroxycarbamates with alfa,beta-Difunctionalised Acrylates
FIORAVANTI, Stefania;MORREALE, Alberto;PELLACANI, Lucio;TARDELLA, Paolo Antonio
2003
Abstract
Highly functionalised aziridines are readily obtained in high yields (up to 95%) under mild conditions from the reaction of trisubstituted olefins bearing different groups with nosyloxycarbamates in the presence of calcium oxide. We propose a possible explanation for the different reactivities observed between these olefins and the aminating agents. Reagent-controlled stereoselective amination reactions led to the expected products with high conversions and purities.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
