The antibacterial activity of extract and isolated ma- jor alkaloids (berberine, b-hydrastine, canadine and canadaline) of Hydrastis canadensis L. (Ranunculaceae) was evaluated against 6 strains of microorganism: Staphylococcus aureus (ATCC 25993 and ATCC 6538P), Streptococcus sanguis (ATCC 10556), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853). Bactericidal activity was evaluated by contact test by measuring the ªkilling timeº on a low density bacterial inoculum, and bacteriostatic activity in liquid medium by M.I.C. values. The results provide a rational basis for the traditional antibacterial use of Hydrastis canadensis.
Antibacterial activity of Hydrastis canadensis extract and its major isolated alkaloids / Scazzocchio, Francesca; M. F., Cometa; Tomassini, Lamberto; Palmery, Maura. - In: PLANTA MEDICA. - ISSN 0032-0943. - STAMPA. - 67:6(2001), pp. 561-564. [10.1055/s-2001-16493]
Antibacterial activity of Hydrastis canadensis extract and its major isolated alkaloids
SCAZZOCCHIO, Francesca;TOMASSINI, Lamberto;PALMERY, Maura
2001
Abstract
The antibacterial activity of extract and isolated ma- jor alkaloids (berberine, b-hydrastine, canadine and canadaline) of Hydrastis canadensis L. (Ranunculaceae) was evaluated against 6 strains of microorganism: Staphylococcus aureus (ATCC 25993 and ATCC 6538P), Streptococcus sanguis (ATCC 10556), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853). Bactericidal activity was evaluated by contact test by measuring the ªkilling timeº on a low density bacterial inoculum, and bacteriostatic activity in liquid medium by M.I.C. values. The results provide a rational basis for the traditional antibacterial use of Hydrastis canadensis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
