A new enantioselective HPLC procedure for the direct semi-preparative resoln. of two unmodified 2-arylpropionic acids is described. The method is based on the use of novel lab.-made chiral stationary phases (CSPs) contg. macrocyclic glycopeptide antibiotics, such as teicoplanin A2-2 and A-40,926, covalently bonded to silica gel microparticles. The new CSPs showed high enantioselectivities and broad applicabilities for sepns. on a semi-preparative scale. [on SciFinder(R)]
Enantioselective semi-preparative HPLC of two arylpropionic acids on glycopeptides containing chiral stationary phases / S., Alcaro; D'Acquarica, Ilaria; Gasparrini, Francesco; Misiti, Domenico; Pierini, Marco; Villani, Claudio. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - STAMPA. - 13:(2002), pp. 69-75. [10.1016/S0957-4166(02)00046-0]
Enantioselective semi-preparative HPLC of two arylpropionic acids on glycopeptides containing chiral stationary phases
D'ACQUARICA, Ilaria;GASPARRINI, Francesco;MISITI, Domenico;PIERINI, MARCO;VILLANI, Claudio
2002
Abstract
A new enantioselective HPLC procedure for the direct semi-preparative resoln. of two unmodified 2-arylpropionic acids is described. The method is based on the use of novel lab.-made chiral stationary phases (CSPs) contg. macrocyclic glycopeptide antibiotics, such as teicoplanin A2-2 and A-40,926, covalently bonded to silica gel microparticles. The new CSPs showed high enantioselectivities and broad applicabilities for sepns. on a semi-preparative scale. [on SciFinder(R)]I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
