The Megasession Technique for Excision of Multiple Neurofibromas

Neurofibromatosis I (NF1), or von Recklinghausen disease, is seen in approximately one in 2,600 to one in 3,000 live births, without preference for race or sex.1 NF causes cosmetic disfigurement. Four types of neurofibromatous lesions exist: cutaneous, subcutaneous, nodular plexiform, and diffuse plexiform. Cutaneous neurofibromas are the most common type; they can vary in number from just a few to several thousand, with the highest density occurring over the trunk. The cutaneous and subcutaneous types are both benign, but a slightly greater risk of malignant transformation exists. Nodular and diffuse plexiform neurofibromas may involve multiple tissues, including skin, fascia, muscle, bone, and internal organs. Patients with multiple cutaneous lesions often feel unattractive and depressed and thus require surgery. Multiple stages are necessary to excise numerous lesions. We reviewed 15 patients with multiple cutaneous neurofibromas treated using a new application for excision of multiple neurofibromasFmegasessionF which consists of a single surgical stage, causes minimal stress for patients, and has good cosmetic result