A total methanolic extract of Ginkgo biloba leaves was fractionated by solvent partition using ethyl acetate (fraction A), n-butanol (fraction B) and water (fraction C). The antimicrobial activity of the three fractions was evaluated using a number of Gram-positive and -negative bacteria and yeasts. The apolar fraction A appeared to be the most interesting because of its activity against several microorganisms; this fraction was further separated by high performance liquid chromatography, and shown to contain substances with strong inhibitory activity against Enterococcus faecalis 31, different from the major known chemical components of G. biloba leaves. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
Antimicrobial investigation of semipurified fractions of Ginkgo biloba leaves / Mazzanti, Gabriela; Mascellino, Maria Teresa; L., Battinelli; D., Coluccia; Manganaro, Mario; Saso, Luciano. - In: JOURNAL OF ETHNOPHARMACOLOGY. - ISSN 0378-8741. - STAMPA. - 71:1-2(2000), pp. 83-88. [10.1016/s0378-8741(99)00179-8]
Antimicrobial investigation of semipurified fractions of Ginkgo biloba leaves
MAZZANTI, Gabriela;MASCELLINO, Maria Teresa;MANGANARO, Mario;SASO, Luciano
2000
Abstract
A total methanolic extract of Ginkgo biloba leaves was fractionated by solvent partition using ethyl acetate (fraction A), n-butanol (fraction B) and water (fraction C). The antimicrobial activity of the three fractions was evaluated using a number of Gram-positive and -negative bacteria and yeasts. The apolar fraction A appeared to be the most interesting because of its activity against several microorganisms; this fraction was further separated by high performance liquid chromatography, and shown to contain substances with strong inhibitory activity against Enterococcus faecalis 31, different from the major known chemical components of G. biloba leaves. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
