Platelets and vascular cells play a fundamental role in the pathogenesis of cardiovascular diseases including thrombus formation and atherosclerotic phenomena. Preparations of platelets and aortic rings have been developed to study the potential of xenobiotics to produce evidence of vascular toxicity in vitro. The xenobiotics cadmium and mercury which exert vascular toxicity in vivo, modify platelet and endothelial-cell reactivity in these in vitro systems
Vascular endothelium and platelet preparations for the prediction of xenobiotic effects on the vascular system / Togna, Giuseppina Ines; Togna, Anna Rita; Caprino, Luciano. - In: XENOBIOTICA. - ISSN 0049-8254. - STAMPA. - 15:8-9(1985), pp. 661-664. [10.3109/00498258509047424]
Vascular endothelium and platelet preparations for the prediction of xenobiotic effects on the vascular system
TOGNA, Giuseppina Ines;TOGNA, Anna Rita;CAPRINO, Luciano
1985
Abstract
Platelets and vascular cells play a fundamental role in the pathogenesis of cardiovascular diseases including thrombus formation and atherosclerotic phenomena. Preparations of platelets and aortic rings have been developed to study the potential of xenobiotics to produce evidence of vascular toxicity in vitro. The xenobiotics cadmium and mercury which exert vascular toxicity in vivo, modify platelet and endothelial-cell reactivity in these in vitro systemsI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.