In developing muscles in vivo and in vitro, the acetylcholine receptor gamma-subunit exists in two splice variants, conferring different single-channel open durations (tau(op)) to reconstituted receptors. In mouse muscles, tau(op) changes around birth possibly as receptors incorporate either variant of gamma-subunit. This might be relevant to the concomitant maturation of muscle innervation.
Functional changes of fetal muscle acetylcholine receptor during mouse development / Grassi, Francesca; Eusebi, Fabrizio. - In: NEWS IN PHYSIOLOGICAL SCIENCES. - ISSN 0886-1714. - STAMPA. - 13:5(1998), pp. 247-251.
Functional changes of fetal muscle acetylcholine receptor during mouse development
GRASSI, Francesca;EUSEBI, Fabrizio
1998
Abstract
In developing muscles in vivo and in vitro, the acetylcholine receptor gamma-subunit exists in two splice variants, conferring different single-channel open durations (tau(op)) to reconstituted receptors. In mouse muscles, tau(op) changes around birth possibly as receptors incorporate either variant of gamma-subunit. This might be relevant to the concomitant maturation of muscle innervation.File allegati a questo prodotto
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