The reaction of azaallylic anions with ethyl N-[4-nitrobenzenesulfonyl)oxy]carbamate in the presence of a base gives a mixture of an alpha-amino ketone derivative with a slight preference for the (S) enantiomer and of an alpha-hydrazino ketone derivative as by-product; the same azaenolates react with bis(tert-butoxycarbonyl)diazene giving the analogous alpha-hydrazino ketone derivative, with a slight preference for the (R) enantiomer.
Amination of Optically Active Azaallylic Anions / Fioravanti, Stefania; L., Olivieri; Pellacani, Lucio; Tardella, Paolo Antonio. - In: JOURNAL OF CHEMICAL RESEARCH. SYNOPSES. - ISSN 0308-2342. - STAMPA. - (1998), pp. 338-339. [10.1039/a709277f]
Amination of Optically Active Azaallylic Anions
FIORAVANTI, Stefania;PELLACANI, Lucio;TARDELLA, Paolo Antonio
1998
Abstract
The reaction of azaallylic anions with ethyl N-[4-nitrobenzenesulfonyl)oxy]carbamate in the presence of a base gives a mixture of an alpha-amino ketone derivative with a slight preference for the (S) enantiomer and of an alpha-hydrazino ketone derivative as by-product; the same azaenolates react with bis(tert-butoxycarbonyl)diazene giving the analogous alpha-hydrazino ketone derivative, with a slight preference for the (R) enantiomer.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
