The effects of acute experimental ocular hypertension on retinal cells have been studied. IOP levels and degree of cell damage have been evaluated by cytochemical and DNA analysis, by which the degeneration, necrotic and apoptotic modalities were observed. Possible pharmacological approaches, e.g. neuroprotection with troxol, have been determined for the prevention of the degenerative events that may be ascribed, at least in part, to oxidizing processes
Apoptotic degeneration induction in retinal cells by acute ocular hypertension and neuroprotection by troxol / Pescosolido, Nicola; Cristofanilli, M.; DE FEO, G.; Risuleo, Gianfranco; Scarsella, Gianfranco. - In: ACTA OPHTHALMOLOGICA SCANDINAVICA. - ISSN 1395-3907. - STAMPA. - 77:229(1999), pp. 8-9. (Intervento presentato al convegno 14th Annual Meeting of the Italian-Association-for-the-Study-Glaucoma tenutosi a RAPALLO, ITALY nel MAR 11-13, 1999).
Apoptotic degeneration induction in retinal cells by acute ocular hypertension and neuroprotection by troxol
PESCOSOLIDO, Nicola;RISULEO, Gianfranco;SCARSELLA, Gianfranco
1999
Abstract
The effects of acute experimental ocular hypertension on retinal cells have been studied. IOP levels and degree of cell damage have been evaluated by cytochemical and DNA analysis, by which the degeneration, necrotic and apoptotic modalities were observed. Possible pharmacological approaches, e.g. neuroprotection with troxol, have been determined for the prevention of the degenerative events that may be ascribed, at least in part, to oxidizing processesI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
