This report shows that glutathione affects ascorbic acid degradation in aqueous solution resulting in a significant stabilization of the vitamin. For the GSH concentrations used in this work the effect was higher on diluted ascorbic acid solutions. It is also shown that for a fixed ascorbic acid concentration, as glutathione concentration increases the degradation reaction shifts from first to zero order.
Glutathione stabilizes ascorbic acid in aqueous solution / E., Touitou; M., Alkebes; Memoli, Adriana; Alhaique, Franco. - In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. - ISSN 0378-5173. - 133:1-2(1996), pp. 85-88. [10.1016/0378-5173(95)04419-1]
Glutathione stabilizes ascorbic acid in aqueous solution
MEMOLI, Adriana;ALHAIQUE, Franco
1996
Abstract
This report shows that glutathione affects ascorbic acid degradation in aqueous solution resulting in a significant stabilization of the vitamin. For the GSH concentrations used in this work the effect was higher on diluted ascorbic acid solutions. It is also shown that for a fixed ascorbic acid concentration, as glutathione concentration increases the degradation reaction shifts from first to zero order.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
