The antimicrobial activity of pure ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rg1), two chemical fractions, and the total extract of Panax ginseng root was investigated. The results showed strong antimicrobial activity (minimum inhibitory concentration <1 μg mL−1) by some pure ginsenosides belonging to both protopanaxadiol and protopanaxatriol groups against representative Gram-positive and Gram-negative bacteria, and yeasts. Conversely, Panax ginseng chemical fractions and the total extract were inactive against the microorganisms tested. This lack of antimicrobial activity may be due to possible antagonist effects between ginsenosides and other Panax ginseng components.
ANTIMICROBIAL ACTIVITY OF GINSENOSIDES / L., Battinelli; Mascellino, Maria Teresa; Martino, Mariaceleste; M., Lu; Mazzanti, Gabriela. - In: PHARMACY AND PHARMACOLOGY COMMUNICATIONS. - ISSN 1460-8081. - STAMPA. - 4:(1998), pp. 411-413. [10.1111/j.2042-7158.1998.tb00721.x]
ANTIMICROBIAL ACTIVITY OF GINSENOSIDES
MASCELLINO, Maria Teresa;MARTINO, Mariaceleste;MAZZANTI, Gabriela
1998
Abstract
The antimicrobial activity of pure ginsenosides (Rb1, Rb2, Rc, Rd, Re, Rg1), two chemical fractions, and the total extract of Panax ginseng root was investigated. The results showed strong antimicrobial activity (minimum inhibitory concentration <1 μg mL−1) by some pure ginsenosides belonging to both protopanaxadiol and protopanaxatriol groups against representative Gram-positive and Gram-negative bacteria, and yeasts. Conversely, Panax ginseng chemical fractions and the total extract were inactive against the microorganisms tested. This lack of antimicrobial activity may be due to possible antagonist effects between ginsenosides and other Panax ginseng components.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
