Phosphatidylcholine (PC), a major membrane phospholipid, is involved in a wide variety of celi functions. Invol vement of PC in signal transduction [i.e., phospholipase D (PLD)-mediated PC hydrolysis] is a well-characterized process, but very little is known about its metabolism after hormonal stimulus. We investigated this process in a weH-characterized experimental system, consisting ofL6 myogenic cells stimulated by Arg8_ vasopressin (AVP), which rapidly activates PLD, inducing measurable PC hydrolysis in the plasma membrane (PM).
HORMONAL REGULATION OF PHOSPHATIDYLCHOLINE METABOLISM AND TRANSPORT / Coletti, Dario; Palleschi, S.; Adamo, Sergio; Silvestroni, Leopoldo. - In: LIPIDS. - ISSN 0024-4201. - STAMPA. - 34:S(1999), pp. 71-71. [10.1007/BF02562233]
HORMONAL REGULATION OF PHOSPHATIDYLCHOLINE METABOLISM AND TRANSPORT
COLETTI, Dario;ADAMO, Sergio;SILVESTRONI, Leopoldo
1999
Abstract
Phosphatidylcholine (PC), a major membrane phospholipid, is involved in a wide variety of celi functions. Invol vement of PC in signal transduction [i.e., phospholipase D (PLD)-mediated PC hydrolysis] is a well-characterized process, but very little is known about its metabolism after hormonal stimulus. We investigated this process in a weH-characterized experimental system, consisting ofL6 myogenic cells stimulated by Arg8_ vasopressin (AVP), which rapidly activates PLD, inducing measurable PC hydrolysis in the plasma membrane (PM).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
