In this work we present a system for the detection of labeled DNA by means of a two-color amorphous silicon photosensor. The device is a p-i-n-i-p structure, whose spectral response is controlled by tuning the voltage applied to its electrodes. The thicknesses of the different layers has been optimized to match the emission spectra of the two utilized fluorochromes. Minima detectable concentrations range in the order of few nmol/l. Very good linearity in the photosensor responses, comparable with those of commercial equipment, has been achieved.

Two-color amorphous silicon photodiode for multicolor detection of labeled DNA / Caputo, Domenico; DE CESARE, Giampiero; Nascetti, Augusto; Negri, Rodolfo; Scipinotti, Riccardo. - 6592:(2007), p. 0C. (Intervento presentato al convegno Microtechnologies for the New Millennium 2007 tenutosi a Maspalomas; Spain nel 02-04 maggio 2007) [10.1117/12.721997].

Two-color amorphous silicon photodiode for multicolor detection of labeled DNA

CAPUTO, Domenico;DE CESARE, Giampiero;NASCETTI, Augusto;NEGRI, RODOLFO;SCIPINOTTI, RICCARDO
2007

Abstract

In this work we present a system for the detection of labeled DNA by means of a two-color amorphous silicon photosensor. The device is a p-i-n-i-p structure, whose spectral response is controlled by tuning the voltage applied to its electrodes. The thicknesses of the different layers has been optimized to match the emission spectra of the two utilized fluorochromes. Minima detectable concentrations range in the order of few nmol/l. Very good linearity in the photosensor responses, comparable with those of commercial equipment, has been achieved.
2007
Microtechnologies for the New Millennium 2007
Amorphous silicon; DNA detection; Label
04 Pubblicazione in atti di convegno::04b Atto di convegno in volume
Two-color amorphous silicon photodiode for multicolor detection of labeled DNA / Caputo, Domenico; DE CESARE, Giampiero; Nascetti, Augusto; Negri, Rodolfo; Scipinotti, Riccardo. - 6592:(2007), p. 0C. (Intervento presentato al convegno Microtechnologies for the New Millennium 2007 tenutosi a Maspalomas; Spain nel 02-04 maggio 2007) [10.1117/12.721997].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/240371
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