Electrochemically induced synthesis of -lactams, by cyclization (via C3 C4 bond formation) of haloamides XCHR1 CONR2 CHR3 R4 (X: Br, Cl), has been achieved in suitable solvent-supporting electrolyte solutions previously electrolyzed under galvanostatic control. The yields and the stereochemistry of the process are affected by the nature of substituents R1 –R4 and of solvent-supporting electrolyte solutions and by the electrolysis conditions.
An electrochemical alternative strategy to the synthesis of beta-lactams. Part 2 [1] C3-C4 Bond formation / Feroci, Marta; Orsini, M; Rossi, L; Sotgiu, G; Inesi, Achille. - In: ELECTROCHIMICA ACTA. - ISSN 0013-4686. - STAMPA. - 51:(2006), pp. 5540-5547. [10.1016/j.electacta.2006.02.026]
An electrochemical alternative strategy to the synthesis of beta-lactams. Part 2 [1] C3-C4 Bond formation.
FEROCI, Marta;INESI, ACHILLE
2006
Abstract
Electrochemically induced synthesis of -lactams, by cyclization (via C3 C4 bond formation) of haloamides XCHR1 CONR2 CHR3 R4 (X: Br, Cl), has been achieved in suitable solvent-supporting electrolyte solutions previously electrolyzed under galvanostatic control. The yields and the stereochemistry of the process are affected by the nature of substituents R1 –R4 and of solvent-supporting electrolyte solutions and by the electrolysis conditions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
