In situ time-resolved energy dispersive x-ray diffraction (EDXD) was applied to investigate the effect of hydration on the structure of 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP)-oriented membranes. The measurements allowed a very high density time sampling of the evolution of the structural properties of the DOTAP bilayer such as the lamellar d-spacing, the membrane thickness, and the size of the interbilayer water region. Time-resolved EDXD has been found to provide important information on the role played by free water molecules on the structure and fluidity of lipid bilayer.
Effect of hydration on the structure of oriented lipid membranes investigated by in situ time-resolved Energy Dispersive X-ray Diffraction / Caminiti, Ruggero; Caracciolo, Giulio; Pisani, M.. - In: APPLIED PHYSICS LETTERS. - ISSN 0003-6951. - STAMPA. - 86:(2005), p. 253902. [10.1063/1.1952583]
Effect of hydration on the structure of oriented lipid membranes investigated by in situ time-resolved Energy Dispersive X-ray Diffraction.
CAMINITI, Ruggero;CARACCIOLO, Giulio;
2005
Abstract
In situ time-resolved energy dispersive x-ray diffraction (EDXD) was applied to investigate the effect of hydration on the structure of 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP)-oriented membranes. The measurements allowed a very high density time sampling of the evolution of the structural properties of the DOTAP bilayer such as the lamellar d-spacing, the membrane thickness, and the size of the interbilayer water region. Time-resolved EDXD has been found to provide important information on the role played by free water molecules on the structure and fluidity of lipid bilayer.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
