Paroxysmal cold haemoglobinuria (PCH) is an autoimmune haemolytic anaemia caused by the Donath-Landsteiner antibody. It is classically described in association with chronic syphilis or after acute viral infections. We describe the first case of PCH presented as a late manifestation of advanced myelofibrosis associated with antiphospholipid syndrome, that promptly responded to high dosage of prednisone.
Paroxysmal cold haemoglobinuria as tardive complication of idiopathic myelofibrosis / Breccia, M; D'Elia, Gm; Girelli, Gabriella; Vaglio, Stefania; Gentilizi, F; Sarlo, C; Alimena, Giuliana. - In: EUROPEAN JOURNAL OF HAEMATOLOGY. - ISSN 0902-4441. - STAMPA. - 73:(2004), pp. 304-306. [10.1111/j.1600-0609.2004.00301.x]
Paroxysmal cold haemoglobinuria as tardive complication of idiopathic myelofibrosis
BRECCIA M;GIRELLI, Gabriella;VAGLIO, Stefania;ALIMENA, Giuliana
2004
Abstract
Paroxysmal cold haemoglobinuria (PCH) is an autoimmune haemolytic anaemia caused by the Donath-Landsteiner antibody. It is classically described in association with chronic syphilis or after acute viral infections. We describe the first case of PCH presented as a late manifestation of advanced myelofibrosis associated with antiphospholipid syndrome, that promptly responded to high dosage of prednisone.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
