We report three cases of invasive Geotrichum capitatum infection in patients with acute leukemia for which an enzyme-linked immunosorbent assay (ELISA) for Aspergillus galactomannan was positive, with no evidence of aspergillosis. Supernatants obtained from suspensions of 17 G. capitatum strains gave positive reactions with the Aspergillus galactomannan ELISA. These clinical and laboratory data seem. to suggest that G. capitatum produces a soluble antigen that is cross-reactive with Aspergillus galactomannan.
Aspergillus galactomannan enzyme-linked immunosorbent assay cross-reactivity caused by invasive Geotrichum capitatum / M., Giacchino; N., Chiapello; S., Bezzio; F., Fagioli; P., Saracco; A., Alfarano; V., Martini; Cimino, Giuseppe; P., Martino; C., Girmenia. - In: JOURNAL OF CLINICAL MICROBIOLOGY. - ISSN 0095-1137. - 44:9(2006), pp. 3432-3434. [10.1128/jcm.00856-06]
Aspergillus galactomannan enzyme-linked immunosorbent assay cross-reactivity caused by invasive Geotrichum capitatum
CIMINO, Giuseppe;
2006
Abstract
We report three cases of invasive Geotrichum capitatum infection in patients with acute leukemia for which an enzyme-linked immunosorbent assay (ELISA) for Aspergillus galactomannan was positive, with no evidence of aspergillosis. Supernatants obtained from suspensions of 17 G. capitatum strains gave positive reactions with the Aspergillus galactomannan ELISA. These clinical and laboratory data seem. to suggest that G. capitatum produces a soluble antigen that is cross-reactive with Aspergillus galactomannan.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.