It is very difficult to find analytical information about nabilone in the literature. To our knowledge this is the first HPLC/MS/MS study of nabilone with a TurboIonSpray source. The method developed here permitted the detection and quantitation of nabilone in bulk powders and capsules. The very good sensitivity (LOD 1⁄4 1 pg of nabilone injected) of the developed method suggests further studies of trace detection of this compound in biological samples using HPLC/MS/ MS, after developing a suitable extraction procedure.
Determination of nabilone in bulk powders and capsules by high-performance liquid chromatography/tandem mass spectrometry / Romolo, Francesco Saverio; Perret, Daniela; LOPEZ CALCAGNINI, Annunziata; Curini, Roberta. - In: RAPID COMMUNICATIONS IN MASS SPECTROMETRY. - ISSN 0951-4198. - STAMPA. - 18:1(2004), pp. 128-130. [10.1002/rcm.1282]
Determination of nabilone in bulk powders and capsules by high-performance liquid chromatography/tandem mass spectrometry
ROMOLO, Francesco Saverio;PERRET, Daniela;LOPEZ CALCAGNINI, Annunziata;CURINI, Roberta
2004
Abstract
It is very difficult to find analytical information about nabilone in the literature. To our knowledge this is the first HPLC/MS/MS study of nabilone with a TurboIonSpray source. The method developed here permitted the detection and quantitation of nabilone in bulk powders and capsules. The very good sensitivity (LOD 1⁄4 1 pg of nabilone injected) of the developed method suggests further studies of trace detection of this compound in biological samples using HPLC/MS/ MS, after developing a suitable extraction procedure.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
