In situ time-resolved energy dispersive X-ray diffraction (EDXD) was applied to investigate the hydration kinetics of oriented dioleoylphosphocoline (DOPC) and 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) membranes. The long-range order in the investigated lipid multilayers has been found to vary as a function of hydration in a nonmonotic way. In the first stage, water adsorption increased the long-range order along the normal to the lipid bilayer whereas, in the second one, a progressive loss of interbilayer coherence was observed. Possible molecular mechanisms underlying the experimental observations are discussed. (c) 2005 Elsevier B.V. All rights reserved.
Effect of hydration on the long-range order of lipid multilayers investigated by in situ time-resolved energy dispersive X-ray diffraction / Caminiti, Ruggero; Caracciolo, Giulio; Michela, Pisani; Paolo, Bruni. - In: CHEMICAL PHYSICS LETTERS. - ISSN 0009-2614. - STAMPA. - 409:4-6(2005), pp. 331-336. [10.1016/j.cplett.2005.05.044]
Effect of hydration on the long-range order of lipid multilayers investigated by in situ time-resolved energy dispersive X-ray diffraction
CAMINITI, Ruggero;CARACCIOLO, Giulio;
2005
Abstract
In situ time-resolved energy dispersive X-ray diffraction (EDXD) was applied to investigate the hydration kinetics of oriented dioleoylphosphocoline (DOPC) and 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) membranes. The long-range order in the investigated lipid multilayers has been found to vary as a function of hydration in a nonmonotic way. In the first stage, water adsorption increased the long-range order along the normal to the lipid bilayer whereas, in the second one, a progressive loss of interbilayer coherence was observed. Possible molecular mechanisms underlying the experimental observations are discussed. (c) 2005 Elsevier B.V. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
