Solid-supported lipid/DNA complexes were prepared by using highly aligned 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) multibilayers as a template. The complex formation was promoted in situ and followed in time. The resulting DOTAP/DNA complex shows a good degree of orientation along the normal to the support as revealed by combined time-resolved energy dispersive X-ray diffraction (EDXD) and surface synchrotron small angle X-ray scattering (SAXS) measurements. © 2005 Elsevier B.V. All rights reserved.
In situ formation of solid-supported lipid/DNA complexes / Caracciolo, Giulio; Heinz, Amenitsch; Sadun, Claudia; Caminiti, Ruggero. - In: CHEMICAL PHYSICS LETTERS. - ISSN 0009-2614. - STAMPA. - 405:4-6(2005), pp. 252-257. [10.1016/j.cplett.2005.02.047]
In situ formation of solid-supported lipid/DNA complexes
CARACCIOLO, Giulio;SADUN, Claudia;CAMINITI, Ruggero
2005
Abstract
Solid-supported lipid/DNA complexes were prepared by using highly aligned 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) multibilayers as a template. The complex formation was promoted in situ and followed in time. The resulting DOTAP/DNA complex shows a good degree of orientation along the normal to the support as revealed by combined time-resolved energy dispersive X-ray diffraction (EDXD) and surface synchrotron small angle X-ray scattering (SAXS) measurements. © 2005 Elsevier B.V. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
