Thymic carcinoma is a relatively uncommon tumor that represents less than 1% of thymic malignancies. The prognosis is often poor, with a 5-year survival for all patients of between 31% and 50%.1 At present, a multimodality approach including aggressive surgical resection, platinum-based combination chemotherapy, and radiotherapy seems the preferred therapeutic strategy. Overall recurrence rate is very high and vascular invasion is particularly associated with poor prognosis. [2] and [3] Only aggressive and complete resection yields long-term survival. We report the management of recurrent thymic carcinoma with extension into the right atrium, resulting from the progression of intracaval growth, 4 years after induction chemotherapy and successful total resection followed by chemoradiation treatment.
Extended operations for recurrent thymic carcinoma presenting with intracaval growth and intracardiac extension / DE GIACOMO, Tiziano; Mazzesi, Giuseppe; Venuta, Federico; Coloni, Giorgio Furio. - In: JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. - ISSN 0022-5223. - STAMPA. - 134(5):(2007), pp. 1364-1365. [10.1016/j.jtcvs.2007.05.066]
Extended operations for recurrent thymic carcinoma presenting with intracaval growth and intracardiac extension
DE GIACOMO, Tiziano;MAZZESI, Giuseppe;VENUTA, Federico;COLONI, Giorgio Furio
2007
Abstract
Thymic carcinoma is a relatively uncommon tumor that represents less than 1% of thymic malignancies. The prognosis is often poor, with a 5-year survival for all patients of between 31% and 50%.1 At present, a multimodality approach including aggressive surgical resection, platinum-based combination chemotherapy, and radiotherapy seems the preferred therapeutic strategy. Overall recurrence rate is very high and vascular invasion is particularly associated with poor prognosis. [2] and [3] Only aggressive and complete resection yields long-term survival. We report the management of recurrent thymic carcinoma with extension into the right atrium, resulting from the progression of intracaval growth, 4 years after induction chemotherapy and successful total resection followed by chemoradiation treatment.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.