Objective To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity. Design Case report. Setting University-based andrology clinic. Patient(s) A 27-year-old man undergoing infertility evaluation. Intervention(s) None. Main outcome measure(s) Serum hormone analysis, standard (World Health Organization) semen quality evaluation, sperm ultrastructure, lymphocytic karyotype, and polymerase chain reaction screening for Y chromosome microdeletions in peripheral blood. Result(s) One hundred percent teratozoospermia characterized by shape alterations of the heads and tail agenesis on standard morphology evaluation, which was confirmed using electron microscopy. Conclusion(s): A case of familial infertility in a consanguineous patient characterized by morphological abnormalities of spermatozoa such as tail agenesis, chromatin subcondensation, and residual cytoplasmic droplets. © 2004 by American Society for Reproductive Medicine.
Sperm tail agenesis in a case of consanguinity / Maurizio, Latini; Gandini, Loredana; Lenzi, Andrea; Romanelli, Francesco. - In: FERTILITY AND STERILITY. - ISSN 0015-0282. - 81:6(2004), pp. 1688-1691. [10.1016/j.fertnstert.2003.10.048]
Sperm tail agenesis in a case of consanguinity
GANDINI, Loredana;LENZI, Andrea;ROMANELLI, Francesco
2004
Abstract
Objective To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity. Design Case report. Setting University-based andrology clinic. Patient(s) A 27-year-old man undergoing infertility evaluation. Intervention(s) None. Main outcome measure(s) Serum hormone analysis, standard (World Health Organization) semen quality evaluation, sperm ultrastructure, lymphocytic karyotype, and polymerase chain reaction screening for Y chromosome microdeletions in peripheral blood. Result(s) One hundred percent teratozoospermia characterized by shape alterations of the heads and tail agenesis on standard morphology evaluation, which was confirmed using electron microscopy. Conclusion(s): A case of familial infertility in a consanguineous patient characterized by morphological abnormalities of spermatozoa such as tail agenesis, chromatin subcondensation, and residual cytoplasmic droplets. © 2004 by American Society for Reproductive Medicine.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
