[GRAPHICS] One-pot aziridinations were obtained starting from substituted 2,2,2-trifluoroethyl beta-dicarbonyl compounds with nosyloxycarbamates in the presence of an excess of CaO as base. The unexpected ring closure reaction takes place at room temperature, leading to the N-protected a-trifluoromethyl aziridines with good yields. The reaction pathway seems to be influenced by the choice of the base.
Unexpected and expeditious entry into trifluoromethyl aziridines from substituted beta-dicarbonyl compounds / Daniele, Colantoni; Fioravanti, Stefania; Pellacani, Lucio; Tardella, Paolo Antonio. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - STAMPA. - 70:23(2005), pp. 9648-9650. [10.1021/jo0515327]
Unexpected and expeditious entry into trifluoromethyl aziridines from substituted beta-dicarbonyl compounds
FIORAVANTI, Stefania;PELLACANI, Lucio;TARDELLA, Paolo Antonio
2005
Abstract
[GRAPHICS] One-pot aziridinations were obtained starting from substituted 2,2,2-trifluoroethyl beta-dicarbonyl compounds with nosyloxycarbamates in the presence of an excess of CaO as base. The unexpected ring closure reaction takes place at room temperature, leading to the N-protected a-trifluoromethyl aziridines with good yields. The reaction pathway seems to be influenced by the choice of the base.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
