A CD band in chiral recognition experiments on racemic stereolabile compounds can be ascribed either to deracemization or to a solely induced CD effect. A procedure is presented that allows one to discriminate positively between the two phenomena. The procedure, based on CD spectroscopy, was used in experiments on racemic biphenylic derivatives in aggregates formed by enantiopure surfactants. In addition to demonstrating a deracemization event, the procedure allowed us to measure the enantiomeric excess.
A new simple procedure for discriminating between deracemization and an induced CD effect in chiral recognition experiments on atropoisomers / Ceccacci, Francesca; Marco, Diociaiuti; Galantini, Luciano; Giovanna, Mancini; Mencarelli, Paolo; Scipioni, Anita; Villani, Claudio. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 6:10(2004), pp. 1565-1568. [10.1021/ol049658y]
A new simple procedure for discriminating between deracemization and an induced CD effect in chiral recognition experiments on atropoisomers
CECCACCI, FRANCESCA;GALANTINI, Luciano;MENCARELLI, Paolo;SCIPIONI, Anita;VILLANI, Claudio
2004
Abstract
A CD band in chiral recognition experiments on racemic stereolabile compounds can be ascribed either to deracemization or to a solely induced CD effect. A procedure is presented that allows one to discriminate positively between the two phenomena. The procedure, based on CD spectroscopy, was used in experiments on racemic biphenylic derivatives in aggregates formed by enantiopure surfactants. In addition to demonstrating a deracemization event, the procedure allowed us to measure the enantiomeric excess.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
