Interferons (IFN) are well known triggers of immunomediated diseases in genetically predisposed subjects. We describe the unique case of a HLAB*2 709 positive subject who underwent IFN-alpha treatment for essential thrombocythentia and developed arthritis of the proximal interphalangeal joints of the hands but not sacroiliitis. The possible mechanisms of IFN-induced arthritis arc, discussed.

HLA-B*2709 and lack of susceptibility to sacroiliitis: further support from the clinic / A., C., A., V., G., D., Fiorillo, M.T., G., P., V., I., V., M., M., P., Sorrentino, R., A., M.. - In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. - ISSN 0392-856X. - 26:6(2008), pp. 1111-1112.

HLA-B*2709 and lack of susceptibility to sacroiliitis: further support from the clinic

FIORILLO, Maria Teresa;SORRENTINO, Rosa;
2008

Abstract

Interferons (IFN) are well known triggers of immunomediated diseases in genetically predisposed subjects. We describe the unique case of a HLAB*2 709 positive subject who underwent IFN-alpha treatment for essential thrombocythentia and developed arthritis of the proximal interphalangeal joints of the hands but not sacroiliitis. The possible mechanisms of IFN-induced arthritis arc, discussed.
2008
ankylosing; ankylosing spondylitis; hla-b*2709; hla-b27; ifn-alpha; ifn-α; sacroiliitis; spondylitis
01 Pubblicazione su rivista::01a Articolo in rivista
HLA-B*2709 and lack of susceptibility to sacroiliitis: further support from the clinic / A., C., A., V., G., D., Fiorillo, M.T., G., P., V., I., V., M., M., P., Sorrentino, R., A., M.. - In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. - ISSN 0392-856X. - 26:6(2008), pp. 1111-1112.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/231529
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