Background: : Individuals with advanced HIV infection naïve to antiretroviral therapy represent a special population of patients frequently encountered in clinical practice. They are at high risk of disease progression and death, and their viroimmunologic response following the initiation of highly active antiretroviral therapy may be more incomplete or slower than that of other patients. Infection management in such patients can also be complicated by underlying conditions, comorbidities, and the need for concomitant medications. Aim: : To provide practical guidelines to those clinicians providing care to HIV-infected patients in terms of diagnostic assessment, monitoring, and treatment. Conclusions: : The principals of antiretroviral treatment in asymptomatic naïve patients with advanced HIV infection are the same as those applicable to the general population with asymptomatic HIV infection. Naïve patients with advanced HIV infection and a history of AIDS-defining illnesses urgently need antiretroviral treatment, with the choice of antiretroviral regimen and timetable based on such factors as concomitant treatment and prophylaxis, drug interactions, and potential concomitant drug toxicity. Finally, an adequate counseling program - both before and after HIV-testing - that includes aspects other than treatment adherence monitoring is a crucial step in disease management. © 2009 Springer.

Italian consensus statement on management of HIV-infected individuals with advanced disease naïve to antiretroviral therapy / A., Antinori; A., Ammassari; C., Torti; P., Marconi; M., Andreoni; G., Angarano; S., Bonora; A., Castagna; R., Cauda; M., Clerici; Ad, Monforte; A., De Luca; G., Di Perri; M., Galli; E., Girardi; A., Gori; A., Lazzarin; S., Lo Caputo; F., Mazzotta; F., Montella; C., Mussini; C. F., Perno; M., Puoti; G., Rizzardini; S., Rusconi; Vullo, Vincenzo; G., Carosi. - In: INFECTION. - ISSN 0300-8126. - 37:3(2009), pp. 270-282. [10.1007/s15010-008-8134-8]

Italian consensus statement on management of HIV-infected individuals with advanced disease naïve to antiretroviral therapy

VULLO, Vincenzo;
2009

Abstract

Background: : Individuals with advanced HIV infection naïve to antiretroviral therapy represent a special population of patients frequently encountered in clinical practice. They are at high risk of disease progression and death, and their viroimmunologic response following the initiation of highly active antiretroviral therapy may be more incomplete or slower than that of other patients. Infection management in such patients can also be complicated by underlying conditions, comorbidities, and the need for concomitant medications. Aim: : To provide practical guidelines to those clinicians providing care to HIV-infected patients in terms of diagnostic assessment, monitoring, and treatment. Conclusions: : The principals of antiretroviral treatment in asymptomatic naïve patients with advanced HIV infection are the same as those applicable to the general population with asymptomatic HIV infection. Naïve patients with advanced HIV infection and a history of AIDS-defining illnesses urgently need antiretroviral treatment, with the choice of antiretroviral regimen and timetable based on such factors as concomitant treatment and prophylaxis, drug interactions, and potential concomitant drug toxicity. Finally, an adequate counseling program - both before and after HIV-testing - that includes aspects other than treatment adherence monitoring is a crucial step in disease management. © 2009 Springer.
2009
01 Pubblicazione su rivista::01a Articolo in rivista
Italian consensus statement on management of HIV-infected individuals with advanced disease naïve to antiretroviral therapy / A., Antinori; A., Ammassari; C., Torti; P., Marconi; M., Andreoni; G., Angarano; S., Bonora; A., Castagna; R., Cauda; M., Clerici; Ad, Monforte; A., De Luca; G., Di Perri; M., Galli; E., Girardi; A., Gori; A., Lazzarin; S., Lo Caputo; F., Mazzotta; F., Montella; C., Mussini; C. F., Perno; M., Puoti; G., Rizzardini; S., Rusconi; Vullo, Vincenzo; G., Carosi. - In: INFECTION. - ISSN 0300-8126. - 37:3(2009), pp. 270-282. [10.1007/s15010-008-8134-8]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/230682
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 10
  • ???jsp.display-item.citation.isi??? 8
social impact