A newborn with a prenatally detected adrenal mass underwent complete resection of it Stage 1 favorable histology neuroblastoma (NB) without MYC-N amplification. Two months later. the infant presented with a local recurrence and multiple hepatic metastases. Close follow-up without therapy was adopted for stage 4s NB. Enlarging tumor lesions were seen until the child was S months old. followed by later decrease in size. At 36 months of follow-up. the child is alive and disease-free. We describe this case of NB and its abnormally short evolution from stage 1 to stage 4s. despite initial surgery. Its Spontaneous regression May help us understand the natural history of congenital NB.
Congenital Stage 1 Neuroblastoma Evolved Into Stage 4s / Schiavetti, Amalia; Micaela, Foco; Annapaola, Ingrosso; Damiano, Chiriaco; Ballesio, Laura. - In: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. - ISSN 1077-4114. - STAMPA. - 31:1(2009), pp. 59-60. [10.1097/mph.0b013e318180bb84]
Congenital Stage 1 Neuroblastoma Evolved Into Stage 4s
SCHIAVETTI, Amalia;BALLESIO, Laura
2009
Abstract
A newborn with a prenatally detected adrenal mass underwent complete resection of it Stage 1 favorable histology neuroblastoma (NB) without MYC-N amplification. Two months later. the infant presented with a local recurrence and multiple hepatic metastases. Close follow-up without therapy was adopted for stage 4s NB. Enlarging tumor lesions were seen until the child was S months old. followed by later decrease in size. At 36 months of follow-up. the child is alive and disease-free. We describe this case of NB and its abnormally short evolution from stage 1 to stage 4s. despite initial surgery. Its Spontaneous regression May help us understand the natural history of congenital NB.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
