This paper describes a microdosimetric study on erythrocytes in two parts: an assessment of the membrane dielectric model from permittivity measurements of erythrocyte solutions and its uncertainty, and a quasi-static electromagnetic (EM) analysis solving the Laplace equation, both analytically and numerically. To evaluate the role of the estimated uncertainty, a stochastic EM solution has been conducted; our results highlight the fundamental role of the dielectric modeling on the reliability of electric field values in the cell membrane. Numerical data, from 3-D cell models, confirm the dependence of the electric field distribution on the extra-cellular field polarization.
A 3-D Microdosimetric Study on Blood Cells: A Permittivity Model of Cell Membrane and Stochastic Electromagnetic Analysis / C., Merla; Liberti, Micaela; Apollonio, Francesca; Nervi, Clara; D'Inzeo, Guglielmo. - In: IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES. - ISSN 0018-9480. - STAMPA. - 58:3(2010), pp. 691-698. [10.1109/tmtt.2010.2040338]
A 3-D Microdosimetric Study on Blood Cells: A Permittivity Model of Cell Membrane and Stochastic Electromagnetic Analysis
LIBERTI, Micaela;APOLLONIO, Francesca;NERVI, Clara;D'INZEO, Guglielmo
2010
Abstract
This paper describes a microdosimetric study on erythrocytes in two parts: an assessment of the membrane dielectric model from permittivity measurements of erythrocyte solutions and its uncertainty, and a quasi-static electromagnetic (EM) analysis solving the Laplace equation, both analytically and numerically. To evaluate the role of the estimated uncertainty, a stochastic EM solution has been conducted; our results highlight the fundamental role of the dielectric modeling on the reliability of electric field values in the cell membrane. Numerical data, from 3-D cell models, confirm the dependence of the electric field distribution on the extra-cellular field polarization.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
