The preparation of palladium nanoparticles stabilized primarily within the protein cavity of a highly thermostable Dps protein (DNA binding protein from starved cells) and the use of this precatalyst system in Suzuki-Miyaura cross-coupling reactions under aerobic conditions in water is described, as well as a two-step one-pot Suzuki-Miyaura cross-coupling followed by an enantioselective enzyme-catalyzed reduction to form chiral biaryl alcohols
Suzuki-Miyaura cross-coupling catalyzed by protein-stabilized palladium nanoparticles under aerobic conditions in water: application to a one-pot chemoenzymatic enantioselective synthesis of chiral biaryl alcohols / A., Prastaro; P., Ceci; E., Chiancone; Boffi, Alberto; R., Cirilli; M., Colone; Fabrizi, Giancarlo; A., Stringaro; Cacchi, Sandro. - In: GREEN CHEMISTRY. - ISSN 1463-9262. - 11:(2009), pp. 1929-1932. [10.1039/b915184b]
Suzuki-Miyaura cross-coupling catalyzed by protein-stabilized palladium nanoparticles under aerobic conditions in water: application to a one-pot chemoenzymatic enantioselective synthesis of chiral biaryl alcohols
BOFFI, Alberto;FABRIZI, Giancarlo;CACCHI, Sandro
2009
Abstract
The preparation of palladium nanoparticles stabilized primarily within the protein cavity of a highly thermostable Dps protein (DNA binding protein from starved cells) and the use of this precatalyst system in Suzuki-Miyaura cross-coupling reactions under aerobic conditions in water is described, as well as a two-step one-pot Suzuki-Miyaura cross-coupling followed by an enantioselective enzyme-catalyzed reduction to form chiral biaryl alcoholsI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
