Contradictory data in the huge literature on microwaves bio-effects may result from a poor understanding of the mechanisms of interaction between microwaves and biological systems. Molecular simulations of biochemical processes seem to be a promising tool to comprehend microwave induced bio-effects. Molecular simulations of classical and quantum events involved in relevant biochemical processes enable to follow the dynamic evolution of a biochemical reaction in the presence of microwave fields. In this paper, the action of a microwave signal (1 GHz) on the covalent binding process of a ligand (carbon monoxide) to a protein (myoglobin) has been studied. Our results indicate that microwave fields, with intensities much below the atomic/molecular electric interactions, cannot affect such biochemical process.

Mixed quantum-classical methods for molecular simulations of biochemical reactions with microwave fields: the case study of myoglobin / Apollonio, Francesca; Liberti, Micaela; Amadei, Andrea; Aschi, Massimiliano; Pellegrino, Monica; D'Alessandro, Maira; D'Abramo, Marco; DI NOLA, Alfredo; D'Inzeo, Guglielmo. - In: IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES. - ISSN 0018-9480. - STAMPA. - 56:11(2008), pp. 2511-2520. [10.1109/TMTT.2008.2005890]

Mixed quantum-classical methods for molecular simulations of biochemical reactions with microwave fields: the case study of myoglobin

APOLLONIO, Francesca;LIBERTI, Micaela;PELLEGRINO, MONICA;D'ALESSANDRO, Maira;D'ABRAMO, Marco;DI NOLA, Alfredo;D'INZEO, Guglielmo
2008

Abstract

Contradictory data in the huge literature on microwaves bio-effects may result from a poor understanding of the mechanisms of interaction between microwaves and biological systems. Molecular simulations of biochemical processes seem to be a promising tool to comprehend microwave induced bio-effects. Molecular simulations of classical and quantum events involved in relevant biochemical processes enable to follow the dynamic evolution of a biochemical reaction in the presence of microwave fields. In this paper, the action of a microwave signal (1 GHz) on the covalent binding process of a ligand (carbon monoxide) to a protein (myoglobin) has been studied. Our results indicate that microwave fields, with intensities much below the atomic/molecular electric interactions, cannot affect such biochemical process.
Bioelectromagnetics; microwaves bio-effects; molecular simulations; myoglobin
01 Pubblicazione su rivista::01a Articolo in rivista
Mixed quantum-classical methods for molecular simulations of biochemical reactions with microwave fields: the case study of myoglobin / Apollonio, Francesca; Liberti, Micaela; Amadei, Andrea; Aschi, Massimiliano; Pellegrino, Monica; D'Alessandro, Maira; D'Abramo, Marco; DI NOLA, Alfredo; D'Inzeo, Guglielmo. - In: IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES. - ISSN 0018-9480. - STAMPA. - 56:11(2008), pp. 2511-2520. [10.1109/TMTT.2008.2005890]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/228345
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