Hypogonadotropic hypogonadism (HH), or secondary hypogonadism, is a clinical condition due to an impairment of the pituitary function, characterized by low testosterone plasma levels associated with normal or low FSH and LH plasma levels. An impairment of gonadotropin secretion and, therefore, a reduced efficiency of spermatogenesis was reported to be frequently associated to conditions different from the classical causes of secondary hypogonadism. These conditions (metabolic, endocrine and eating disorders, physical exercise etc.) have been associated with a non-classical form of HH that could be called "functional" HH (FHH). FHH differs from the classical one by the evidence that gonadotropin levels are in the low-normal range, but are inadequate for the testosterone levels, that often are also in the low-normal range. This commentary aims at reviewing knowledge on the forms of male HH in order to indicate and discuss clinical context, diagnostic and therapeutic approach in the less known non-classical form, i.e. FHH. (J. Endocrinol. Invest. 32: 934-938, 2009) (C) 2009, Editrice Kurtis

Epidemiology, diagnosis, and treatment of male hypogonadotropic hypogonadism / Lenzi, Andrea; G., Balercia; A., Bellastella; A., Colao; A., Fabbri; C., Foresta; M., Galdiero; Gandini, Loredana; C., Krausz; G., Lombardi; Lombardo, Francesco; M., Maggi; Radicioni, Antonio; R., Selice; A. A., Sinisi; G., Forti. - In: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. - ISSN 0391-4097. - 32:11(2009), pp. 934-938. [10.3275/6714]

Epidemiology, diagnosis, and treatment of male hypogonadotropic hypogonadism

LENZI, Andrea;GANDINI, Loredana;LOMBARDO, Francesco;RADICIONI, Antonio;
2009

Abstract

Hypogonadotropic hypogonadism (HH), or secondary hypogonadism, is a clinical condition due to an impairment of the pituitary function, characterized by low testosterone plasma levels associated with normal or low FSH and LH plasma levels. An impairment of gonadotropin secretion and, therefore, a reduced efficiency of spermatogenesis was reported to be frequently associated to conditions different from the classical causes of secondary hypogonadism. These conditions (metabolic, endocrine and eating disorders, physical exercise etc.) have been associated with a non-classical form of HH that could be called "functional" HH (FHH). FHH differs from the classical one by the evidence that gonadotropin levels are in the low-normal range, but are inadequate for the testosterone levels, that often are also in the low-normal range. This commentary aims at reviewing knowledge on the forms of male HH in order to indicate and discuss clinical context, diagnostic and therapeutic approach in the less known non-classical form, i.e. FHH. (J. Endocrinol. Invest. 32: 934-938, 2009) (C) 2009, Editrice Kurtis
2009
fsh; functional hypogonadotropic hypogonadism; functional hypogoradotropic hypogonadism; hypogonadotropic hypogonadism; male infertility; testosterone
01 Pubblicazione su rivista::01a Articolo in rivista
Epidemiology, diagnosis, and treatment of male hypogonadotropic hypogonadism / Lenzi, Andrea; G., Balercia; A., Bellastella; A., Colao; A., Fabbri; C., Foresta; M., Galdiero; Gandini, Loredana; C., Krausz; G., Lombardi; Lombardo, Francesco; M., Maggi; Radicioni, Antonio; R., Selice; A. A., Sinisi; G., Forti. - In: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. - ISSN 0391-4097. - 32:11(2009), pp. 934-938. [10.3275/6714]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/227821
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