Optically active (E)-nitro alkenes carrying a 1,3-dioxolane or 1,3-oxazolidine residue undergo stereoselective aza-MIRC reactions, leading to the synthesis of the corresponding chiral nitro aziridines in high yields and with good diastereoselectivity. Interestingly, the stereochemical outcome of the aziridination reactions was strongly influenced by the chiral residue considered, giving stereoisomers, regardless of the reaction conditions. © 2008 Elsevier Ltd. All rights reserved.
Stereoselective aza-MIRC reactions on optically active (E)-nitro alkenes / Fioravanti, Stefania; Fabio, Marchetti; Pellacani, Lucio; Ranieri, Luca; Tardella, Paolo Antonio. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - STAMPA. - 19:2(2008), pp. 231-236. [10.1016/j.tetasy.2007.12.007]
Stereoselective aza-MIRC reactions on optically active (E)-nitro alkenes
FIORAVANTI, Stefania;PELLACANI, Lucio;RANIERI, LUCA;TARDELLA, Paolo Antonio
2008
Abstract
Optically active (E)-nitro alkenes carrying a 1,3-dioxolane or 1,3-oxazolidine residue undergo stereoselective aza-MIRC reactions, leading to the synthesis of the corresponding chiral nitro aziridines in high yields and with good diastereoselectivity. Interestingly, the stereochemical outcome of the aziridination reactions was strongly influenced by the chiral residue considered, giving stereoisomers, regardless of the reaction conditions. © 2008 Elsevier Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
