Innovative hydrogels obtained by physical and chemical crosslinking of deacylated Gellan gum have been characterized in terms of water uptake, rheological properties and compressibility, and the behaviour of the tested materials, according to the type of the obtained network, is thoroughly discussed. The release from the various gels of loaded model molecules of different steric hindrance was also investigated and the trend of the release profiles has been related to the structures proposed for the physical and the chemical hydrogel.

Preparation and Characterization of Novel Gellan Gum Hydrogels Suitable for Modified Drug Release / Matricardi, Pietro; Claudia, Cencetti; Roberto, Ria; Alhaique, Franco; Coviello, Tommasina. - In: MOLECULES. - ISSN 1420-3049. - 14:9(2009), pp. 3376-3391. [10.3390/molecules14093376]

Preparation and Characterization of Novel Gellan Gum Hydrogels Suitable for Modified Drug Release

MATRICARDI, PIETRO;ALHAIQUE, Franco;COVIELLO, Tommasina
2009

Abstract

Innovative hydrogels obtained by physical and chemical crosslinking of deacylated Gellan gum have been characterized in terms of water uptake, rheological properties and compressibility, and the behaviour of the tested materials, according to the type of the obtained network, is thoroughly discussed. The release from the various gels of loaded model molecules of different steric hindrance was also investigated and the trend of the release profiles has been related to the structures proposed for the physical and the chemical hydrogel.
2009
gellan; hydrogels; modified drug release; rheology; texture analysis
01 Pubblicazione su rivista::01a Articolo in rivista
Preparation and Characterization of Novel Gellan Gum Hydrogels Suitable for Modified Drug Release / Matricardi, Pietro; Claudia, Cencetti; Roberto, Ria; Alhaique, Franco; Coviello, Tommasina. - In: MOLECULES. - ISSN 1420-3049. - 14:9(2009), pp. 3376-3391. [10.3390/molecules14093376]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/226088
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