Uterine carcinosarcoma is a highly aggressive neoplasm with tendency to early recurrence and/or metastasis. The neoplasia has both epithelial and stromal malignant components. Clinically, it is characterized by a postmenopausal metrorrhagia, associated sometimes with abdominal pain. The Authors describe a case of carcinosarcoma in a 82-year old woman with a vaginal bleeding since 10 months and an ingravescent hypochromic anemia. The RMN of the abdomen and pelvis showed a mass occupying the whole uterine lumen, without signs of pelvic diffusion. A bilateral hystero-oophorectomy was performed; the patient's critical conditions and a high anaesthesiological risk advised us not to perform a bilateral pelvic lymphadenectomy with aortic sampling. Six months after operation, a clinical follow-up with a total-body CT didn't show any sign of local recurrence and/or distant metastasis. From the analysis of this case report and from the data of the literature some important considerations can be done: a) gynecologic check up in post-menopausal women with associated risk factors (obesity and hypertension) can allow an early diagnosis also in asymptomatic patients; b) sovrapubic and transvaginal US, abdomino-pelvic CT and MRI are essential for a correct clinical staging; c) surgical excision followed by the histological examination of the specimen is mandatory to establish a correct diagnosis.

A case of uterine carcinosarcoma / Spaziani, Erasmo; Stagnitti, Franco; Picchio, M; DI FILIPPO, Annalisa Romina; Petrozza, Vincenzo; Censi, F; Sardella, B; Briganti, M; Ceci, F; Nicodemi, S; Nardecchia, G; DE ANGELIS, F; Cipriani, B.. - In: IL GIORNALE DI CHIRURGIA. - ISSN 0391-9005. - STAMPA. - 29:8-9(2008), pp. 365-368.

A case of uterine carcinosarcoma

SPAZIANI, Erasmo;STAGNITTI, Franco;DI FILIPPO, Annalisa Romina;PETROZZA, Vincenzo;DE ANGELIS F;
2008

Abstract

Uterine carcinosarcoma is a highly aggressive neoplasm with tendency to early recurrence and/or metastasis. The neoplasia has both epithelial and stromal malignant components. Clinically, it is characterized by a postmenopausal metrorrhagia, associated sometimes with abdominal pain. The Authors describe a case of carcinosarcoma in a 82-year old woman with a vaginal bleeding since 10 months and an ingravescent hypochromic anemia. The RMN of the abdomen and pelvis showed a mass occupying the whole uterine lumen, without signs of pelvic diffusion. A bilateral hystero-oophorectomy was performed; the patient's critical conditions and a high anaesthesiological risk advised us not to perform a bilateral pelvic lymphadenectomy with aortic sampling. Six months after operation, a clinical follow-up with a total-body CT didn't show any sign of local recurrence and/or distant metastasis. From the analysis of this case report and from the data of the literature some important considerations can be done: a) gynecologic check up in post-menopausal women with associated risk factors (obesity and hypertension) can allow an early diagnosis also in asymptomatic patients; b) sovrapubic and transvaginal US, abdomino-pelvic CT and MRI are essential for a correct clinical staging; c) surgical excision followed by the histological examination of the specimen is mandatory to establish a correct diagnosis.
2008
01 Pubblicazione su rivista::01a Articolo in rivista
A case of uterine carcinosarcoma / Spaziani, Erasmo; Stagnitti, Franco; Picchio, M; DI FILIPPO, Annalisa Romina; Petrozza, Vincenzo; Censi, F; Sardella, B; Briganti, M; Ceci, F; Nicodemi, S; Nardecchia, G; DE ANGELIS, F; Cipriani, B.. - In: IL GIORNALE DI CHIRURGIA. - ISSN 0391-9005. - STAMPA. - 29:8-9(2008), pp. 365-368.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/226053
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