Purpose: To assess 1H-magnetic resonance spectroscopic imaging (1H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI) features in histologically confirmed prostatic chronic inflammation, prostatic intraepithelial neoplasia (PIN), low grade prostate cancer (LGPCa), and high grade prostate cancer (HGPCa). Materials and Methods: Ninety-six men were selected, who showed at histology a diagnosis of chronic inflammation (Group B), high grade (HG) PIN (Group C), or prostate cancer (LGPCa Group D and HGPCa Group E). Results: ANOVA analysis shows that inflammation (Group B) displays no significantly (p >.05) different choline and citrate levels when compared to HGPIN and LGPCa. Conclusion: our results suggest the potential for these MR imaging techniques in the description of inflammatory and proliferative lesions inside the prostate gland. Copyright © 2010 Informa Healthcare USA, Inc.
Magnetic resonance spectroscopic imaging (1H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI): Pattern changes from inflammation to prostate cancer / Sciarra, Alessandro; Panebianco, Valeria; Ciccariello, Mauro; Salciccia, Stefano; Lisi, Danilo; Osimani, Marcello; Alfarone, Andrea; Gentilucci, Alessandro; Parente, Ulderico; Passariello, Roberto; Gentile, Vincenzo. - In: CANCER INVESTIGATION. - ISSN 0735-7907. - 28:4(2010), pp. 424-432. [10.1080/07357900903287048]
Magnetic resonance spectroscopic imaging (1H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI): Pattern changes from inflammation to prostate cancer
SCIARRA, Alessandro;PANEBIANCO, VALERIA;CICCARIELLO, Mauro;SALCICCIA, STEFANO;LISI, DANILO;OSIMANI, MARCELLO;ALFARONE, ANDREA;GENTILUCCI, ALESSANDRO;PARENTE, ULDERICO;PASSARIELLO, Roberto;GENTILE, Vincenzo
2010
Abstract
Purpose: To assess 1H-magnetic resonance spectroscopic imaging (1H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI) features in histologically confirmed prostatic chronic inflammation, prostatic intraepithelial neoplasia (PIN), low grade prostate cancer (LGPCa), and high grade prostate cancer (HGPCa). Materials and Methods: Ninety-six men were selected, who showed at histology a diagnosis of chronic inflammation (Group B), high grade (HG) PIN (Group C), or prostate cancer (LGPCa Group D and HGPCa Group E). Results: ANOVA analysis shows that inflammation (Group B) displays no significantly (p >.05) different choline and citrate levels when compared to HGPIN and LGPCa. Conclusion: our results suggest the potential for these MR imaging techniques in the description of inflammatory and proliferative lesions inside the prostate gland. Copyright © 2010 Informa Healthcare USA, Inc.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
