XANES spectra of non structural protein 3 (NS3) have been calculated using 4 Zn coordination models from three crystallographic structures in the Protein Data Base (PDB): 1DY9, subunit B, 1CU1 subunit A and B, and 1JXP subunit B. Results indicate that XANES is an appropriate tool to distinguish among them. Experimental XANES spectra have been simulated refining crystallographic data. The model obtained by XAS is compared with the PDB models. © 2007 American Institute of Physics.
XAS characterization of the Zn site of non-structural protein 3 (NS3) from hepatitis C virus / I., Ascone; G., Nobili; M., Benfatto; CONGIU, Agostina. - In: AIP CONFERENCE PROCEEDINGS. - ISSN 0094-243X. - 882:(2007), pp. 319-321. (Intervento presentato al convegno X-RAY ABSORPTION FINE STRUCTURE - XAFS13: 13th International Conference tenutosi a Stanford; United States nel 9 July 2006 through 14 July 2006) [10.1063/1.2644511].
XAS characterization of the Zn site of non-structural protein 3 (NS3) from hepatitis C virus
CONGIU, Agostina
2007
Abstract
XANES spectra of non structural protein 3 (NS3) have been calculated using 4 Zn coordination models from three crystallographic structures in the Protein Data Base (PDB): 1DY9, subunit B, 1CU1 subunit A and B, and 1JXP subunit B. Results indicate that XANES is an appropriate tool to distinguish among them. Experimental XANES spectra have been simulated refining crystallographic data. The model obtained by XAS is compared with the PDB models. © 2007 American Institute of Physics.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.