The third component of complement has been shown to be involved in a number of biological functions. It acts through interaction with specific receptors or covalent interaction with acceptor sites on cell membranes. The aim of this work is to determine the traffic and the subcellular distribution of C3 in Lewis lung carcinoma (3LL). Cytofluorimetric studies showed that C3 molecules bound to 3LL cells after incubation in normal murine serum decreased from the cell surface and internalized by a time dependent process. This finding was confirmed by electron microscopic investigation.

Compartimentalization of the third component of complement (C3) in 3LL murine carcinoma cells, studied by immunogold labeling / Morgante, E.; DI RENZO, Livia Maria; Longo, A.; Cunsolo, M. G.; Lipari, M.; Pontieri, G. M.; Russo, M. A.. - STAMPA. - (1997), pp. 135-139. (Intervento presentato al convegno 2nd International Malpighi symposium on recent advances in microscopy of cells tissues and organs. tenutosi a Rome; Italy nel 14-16 Settembre 1995).

Compartimentalization of the third component of complement (C3) in 3LL murine carcinoma cells, studied by immunogold labeling

DI RENZO, Livia Maria;
1997

Abstract

The third component of complement has been shown to be involved in a number of biological functions. It acts through interaction with specific receptors or covalent interaction with acceptor sites on cell membranes. The aim of this work is to determine the traffic and the subcellular distribution of C3 in Lewis lung carcinoma (3LL). Cytofluorimetric studies showed that C3 molecules bound to 3LL cells after incubation in normal murine serum decreased from the cell surface and internalized by a time dependent process. This finding was confirmed by electron microscopic investigation.
1997
2nd International Malpighi symposium on recent advances in microscopy of cells tissues and organs.
lewis lung carcinoma; c3 complement; immunolocalization
04 Pubblicazione in atti di convegno::04b Atto di convegno in volume
Compartimentalization of the third component of complement (C3) in 3LL murine carcinoma cells, studied by immunogold labeling / Morgante, E.; DI RENZO, Livia Maria; Longo, A.; Cunsolo, M. G.; Lipari, M.; Pontieri, G. M.; Russo, M. A.. - STAMPA. - (1997), pp. 135-139. (Intervento presentato al convegno 2nd International Malpighi symposium on recent advances in microscopy of cells tissues and organs. tenutosi a Rome; Italy nel 14-16 Settembre 1995).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/180430
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