We present an electromechanical model of myocardium tissue, coupling finite elasticity, endowed with the capability of describing muscle contractions, with a FitzHugh–Nagumo type system, describing the electrical activity proper to excitable media. Here, we exploit a novel point of view which introduces the notion of active deformation as opposed to that of active stress. The high degree of deformability of the medium makes mandatory to set the diffusion process in a moving domain, thereby producing a direct influence of the deformation on the electrical activity. Various effects of contraction on stationary rotating spiral waves and spiral wave break up are discussed.

Electromechanical modelling of cardiac tissues / Cherubini, C; Filippi, S; Nardinocchi, Paola; Teresi, L.. - STAMPA. - 3(2010), pp. 421-449. [10.1007/978-90-481-2850-1].

Electromechanical modelling of cardiac tissues

NARDINOCCHI, Paola;
2010

Abstract

We present an electromechanical model of myocardium tissue, coupling finite elasticity, endowed with the capability of describing muscle contractions, with a FitzHugh–Nagumo type system, describing the electrical activity proper to excitable media. Here, we exploit a novel point of view which introduces the notion of active deformation as opposed to that of active stress. The high degree of deformability of the medium makes mandatory to set the diffusion process in a moving domain, thereby producing a direct influence of the deformation on the electrical activity. Various effects of contraction on stationary rotating spiral waves and spiral wave break up are discussed.
2010
Mechanosensitivity in Cells and Tissues: Mechanosensitivity of the Heart
9789048128495
Electromechanics; Mechanoelectric feedback; Mathematical physiology
02 Pubblicazione su volume::02a Capitolo o Articolo
Electromechanical modelling of cardiac tissues / Cherubini, C; Filippi, S; Nardinocchi, Paola; Teresi, L.. - STAMPA. - 3(2010), pp. 421-449. [10.1007/978-90-481-2850-1].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/178833
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