The electrophysiological features of wake and sleep in neurodegenerations show alterations compared to healthy aging, in direction of slowing of the waking EEG and reduction of frequencies power during sleep. While the falling asleep process (Sleep Onset, SO) has been recently described in healthy aging, the features of SO in Alzheimer (AD) and Mild Cognitive Impairment (MCI) are still lacking. The present study aims to depict the spatiotemporal dynamics of SO in these patients compared to Healthy Controls (HC).
Sleep Onset Process in Neurodegenerations: How Mild Cognitive Impairment and Alzheimer Fall Asleep / Annarumma, L., Scarpelli, S., Alfonsi, V., De Gennaro, L., Gorgoni, M.. - In: JOURNAL OF SLEEP RESEARCH. - ISSN 0962-1105. - 35:S1(2026). [10.1111/jsr.70435]
Sleep Onset Process in Neurodegenerations: How Mild Cognitive Impairment and Alzheimer Fall Asleep
Ludovica Annarumma;Serena Scarpelli;Luigi De Gennaro;Maurizio Gorgoni
2026
Abstract
The electrophysiological features of wake and sleep in neurodegenerations show alterations compared to healthy aging, in direction of slowing of the waking EEG and reduction of frequencies power during sleep. While the falling asleep process (Sleep Onset, SO) has been recently described in healthy aging, the features of SO in Alzheimer (AD) and Mild Cognitive Impairment (MCI) are still lacking. The present study aims to depict the spatiotemporal dynamics of SO in these patients compared to Healthy Controls (HC).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
