Radiative oncological hyperthermia (HT) employs electromagnetic (EM) fields to deliver controlled heating to tumor tissue, raising its temperature up to 40-44 °C for therapeutic effect. Electric field (E-field) sensors can be a valuable tool for verifying the EM distribution delivered by an HT device. In this work, a temperature-based calibration procedure for an E-field sensor designed for superficial hyperthermia (sHT) applications is presented. The method relies on simultaneous measurement of the sensor output voltage (Vout) and the temperature rise (ΔT) at a fixed position in a tissue-equivalent phantom. The E-field amplitude is derived from the temperature increase under short-time irradiation. An experimental setup was realized using a commercial sHT antenna, working at 434 MHz, on a curved phantom filled with a tissue-equivalent solution. Measurements were performed at power levels up to 100 W, with the E-field sensor and a fiber-optic temperature probe at 1 cm depth inside the phantom to monitor Vout and ΔT, respectively. The temperature evolution was analyzed to identify the suitable time interval for calibration. All uncertainty contributions were assessed, and the analysis of the overall method uncertainty is reported.
Temperature-Based Calibration of E-Field Sensor for Superficial Hyperthermia / Di Cristofano, M., Giuppa, F., Rodio, C., Cavagnaro, M.. - (2026), pp. 57-61. (9th IEEE International Workshop on Metrology for Industry 4.0 and IoT, MetroInd4.0 and IoT 2026 Universita Campus Bio-Medico di Roma (UCBM), ita ) [10.1109/MetroInd4.0IoT69397.2026.11653063].
Temperature-Based Calibration of E-Field Sensor for Superficial Hyperthermia
Di Cristofano M.;Cavagnaro M.
2026
Abstract
Radiative oncological hyperthermia (HT) employs electromagnetic (EM) fields to deliver controlled heating to tumor tissue, raising its temperature up to 40-44 °C for therapeutic effect. Electric field (E-field) sensors can be a valuable tool for verifying the EM distribution delivered by an HT device. In this work, a temperature-based calibration procedure for an E-field sensor designed for superficial hyperthermia (sHT) applications is presented. The method relies on simultaneous measurement of the sensor output voltage (Vout) and the temperature rise (ΔT) at a fixed position in a tissue-equivalent phantom. The E-field amplitude is derived from the temperature increase under short-time irradiation. An experimental setup was realized using a commercial sHT antenna, working at 434 MHz, on a curved phantom filled with a tissue-equivalent solution. Measurements were performed at power levels up to 100 W, with the E-field sensor and a fiber-optic temperature probe at 1 cm depth inside the phantom to monitor Vout and ΔT, respectively. The temperature evolution was analyzed to identify the suitable time interval for calibration. All uncertainty contributions were assessed, and the analysis of the overall method uncertainty is reported.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
