Background Sulphurous thermal waters (STW) are known for their wound-healing properties, attributed not only to dissolved minerals but also to hydrogen sulfide (H₂S), a gas transmitter that diffuses through the skin, exerting local and systemic effects. H₂S promotes healing in acute, chronic, and infected wounds and contributes to eutrophic scarring post healing. The specific microbiome of sulphurous springs may also interact with the skin microbiome, restoring eubiosis and reducing biofilm formation.
Randomized pilot trial on the effects of H₂S-based wound hygiene in hard to heal wounds: the SPA wound care / Crucianelli, S., Mariano, A., Barile, D., Moretti, F., Valeriani, F., Sisto, A., Campoli, A., Romano Spica, V., Ciprandi, G., Fontana, M.. - (2026), pp. 239-239. (WUWHS 2026. World union of wound healing societies. Global paradigm shift: wound care specialty & recognition Kuala Lumpur, Malaysia ).
Randomized pilot trial on the effects of H₂S-based wound hygiene in hard to heal wounds: the SPA wound care
Serena Crucianelli
;Alessia Mariano;Denise Barile;Ferdinando Moretti;Federica Valeriani;Guido Ciprandi;Mario Fontana
2026
Abstract
Background Sulphurous thermal waters (STW) are known for their wound-healing properties, attributed not only to dissolved minerals but also to hydrogen sulfide (H₂S), a gas transmitter that diffuses through the skin, exerting local and systemic effects. H₂S promotes healing in acute, chronic, and infected wounds and contributes to eutrophic scarring post healing. The specific microbiome of sulphurous springs may also interact with the skin microbiome, restoring eubiosis and reducing biofilm formation.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
