Coronavirus disease 2019 (COVID-19) led to extensive morbidity and mortality. Attention is shifting to long-term effects persisting after acute infection, termed long/post–COVID-19, including cardiac sequelae.1 Cardiovascular magnetic resonance (CMR) abnormality is present at 6-month follow-up in half of patients recovered from COVID-19 with in-hospital high-sensitivity troponin elevation.2 Lack of preinfection data renders it hard to exclude causality from pre-existing conditions, rather than infection sequelae. Yet larger studies show increased risk of incident cardiovascular disease in the year after COVID-19,3,4 suggesting that long/post–COVID-19 cardiac sequelae may become a major public health issue.
Long COVID-19 Cardiac Complications Are Associated With Autoimmunity to Cardiac Self-Antigens Sufficient to Cause Cardiac Dysfunction / Cremonesi, M., Felicetta, A., Cannata, F., Serio, S., Van Beek, J.J.P., Bombace, S., My, I., Zanon, V., Catalano, C., Papadopoulou, V., Monti, L., Chiarito, M., Stefanini, G., Panico, C., Francone, M., Lugli, E., Kallikourdis, M., Condorelli, G.. - In: CIRCULATION. - ISSN 0009-7322. - 148:6(2023), pp. 504-507. [10.1161/CIRCULATIONAHA.122.062672]
Long COVID-19 Cardiac Complications Are Associated With Autoimmunity to Cardiac Self-Antigens Sufficient to Cause Cardiac Dysfunction
Cannata F.;Serio S.;Papadopoulou V.;Stefanini G.;Francone M.;Lugli E.;Kallikourdis M.;Condorelli G.
2023
Abstract
Coronavirus disease 2019 (COVID-19) led to extensive morbidity and mortality. Attention is shifting to long-term effects persisting after acute infection, termed long/post–COVID-19, including cardiac sequelae.1 Cardiovascular magnetic resonance (CMR) abnormality is present at 6-month follow-up in half of patients recovered from COVID-19 with in-hospital high-sensitivity troponin elevation.2 Lack of preinfection data renders it hard to exclude causality from pre-existing conditions, rather than infection sequelae. Yet larger studies show increased risk of incident cardiovascular disease in the year after COVID-19,3,4 suggesting that long/post–COVID-19 cardiac sequelae may become a major public health issue.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
