SENSIPLUS microchip for biomedical impedance measurements

Recent advancements in telemedicine and personalized healthcare have highlighted the need for accurate, non-invasive physiological monitoring tools. Bioimpedance analysis (BIA) has emerged as a powerful technique for assessing body composition and other physiological conditions. This study evaluates the SENSIPLUS chip, developed by Sensichips s.r.l., as a compact and low-power solution for bioimpedance spectroscopy. Integrated into the MicroAnalytical Tool (MAT), the chip performs low-noise impedance measurements up to 2.5 MHz using adhesive electrodes in a tetrapolar configuration. Measurements were conducted on a volunteer over the 10 kHz–1 MHz range and fitted using the Cole-Cole model to extract physiologically relevant parameters. A correction method was introduced to mitigate parasitic capacitance effects, enhancing high-frequency accuracy. Results showed strong agreement with a reference LCR meter and excellent measurement repeatability. These findings confirm the feasibility of the SENSIPLUS chip for reliable, non-invasive body composition analysis and support its integration into IoMT-enabled healthcare systems for continuous, remote diagnostics.