Over the past decade, significant progress has been made in understanding eosinophilic oesophagitis (EoE), leading to the refinement of diagnostic criteria and the development of evidence-based management guidelines. Nevertheless, despite the central role of histology in both diagnosis and disease monitoring, significant variability remains in histopathological reporting across institutions and among pathologists.This study seeks to provide recommendations for standardised histological reporting in EoE. To this end, a multidisciplinary panel of gastroenterologists and pathologists convened to review current practices and address persistent challenges in histologic assessment. Through an extensive literature review and critical appraisal of existing scoring systems, the panel reached consensus on both essential and desirable histological features for routine reporting, including eosinophil counts, additional inflammatory parameters, and fibrostenotic changes.

Standardisation of histologic reporting in eosinophilic oesophagitis: Expert recommendations / Giordano, Carla; Angerilli, Valentina; Masci, Marco; D'Armiento, Maria; Parente, Paola; Pilozzi, Emanuela; Vanoli, Alessandro; Oliva, Salvatore; Savarino, Edoardo Vincenzo; Fassan, Matteo; Mastracci, Luca. - In: PATHOLOGICA. - ISSN 1591-951X. - 118:1(2026), pp. 4-14. [10.32074/1591-951x-1842]

Standardisation of histologic reporting in eosinophilic oesophagitis: Expert recommendations

Giordano, Carla
Primo
;
Pilozzi, Emanuela;Oliva, Salvatore;
2026

Abstract

Over the past decade, significant progress has been made in understanding eosinophilic oesophagitis (EoE), leading to the refinement of diagnostic criteria and the development of evidence-based management guidelines. Nevertheless, despite the central role of histology in both diagnosis and disease monitoring, significant variability remains in histopathological reporting across institutions and among pathologists.This study seeks to provide recommendations for standardised histological reporting in EoE. To this end, a multidisciplinary panel of gastroenterologists and pathologists convened to review current practices and address persistent challenges in histologic assessment. Through an extensive literature review and critical appraisal of existing scoring systems, the panel reached consensus on both essential and desirable histological features for routine reporting, including eosinophil counts, additional inflammatory parameters, and fibrostenotic changes.
2026
Eosinophilic oesophagitis; follow-up; histopathology; standardisation; diagnosis
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Standardisation of histologic reporting in eosinophilic oesophagitis: Expert recommendations / Giordano, Carla; Angerilli, Valentina; Masci, Marco; D'Armiento, Maria; Parente, Paola; Pilozzi, Emanuela; Vanoli, Alessandro; Oliva, Salvatore; Savarino, Edoardo Vincenzo; Fassan, Matteo; Mastracci, Luca. - In: PATHOLOGICA. - ISSN 1591-951X. - 118:1(2026), pp. 4-14. [10.32074/1591-951x-1842]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1765439
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