Electrospun nanofibrous coatings based on poly(lactic acid) (PLA) and bioactive nano-hydroxyapatite (nHAp) are developed to enhance the biocompatibility and corrosion resistance of titanium implants for medical applications. The electrospinning process parameters are optimized to achieve a uniform morphology of PLA nanofibers and PLA/nHAp composite fibers. The morphology and porosity of the fiber coatings were investigated by scanning electron microscopy. FTIR spectroscopy confirms the successful incorporation of nHAp into the PLA fibers, while electrochemical impedance spectroscopy demonstrates a significant improvement in corrosion resistance for the nanocomposite-coated titanium. Results show that the PLA/nHAp composite coatings prepared by electrospinning have promising features for applications in orthopedic and dental implantology.
Nanofibrous Coatings of Poly(Lactic Acid) and Nano‐Hydroxyapatite for Enhanced Biocompatibility of Titanium Implants / Ciarleglio, Gianluca; Pagani, Letizia; Ferri, Lorenzo; Toto, Elisa; Santonicola, Maria Gabriella. - In: MACROMOLECULAR SYMPOSIA. - ISSN 1022-1360. - (2025), pp. 1-3. [10.1002/masy.70248]
Nanofibrous Coatings of Poly(Lactic Acid) and Nano‐Hydroxyapatite for Enhanced Biocompatibility of Titanium Implants
Ciarleglio, Gianluca
Primo
;Pagani, Letizia;Ferri, Lorenzo;Toto, Elisa;Santonicola, Maria Gabriella
Ultimo
2025
Abstract
Electrospun nanofibrous coatings based on poly(lactic acid) (PLA) and bioactive nano-hydroxyapatite (nHAp) are developed to enhance the biocompatibility and corrosion resistance of titanium implants for medical applications. The electrospinning process parameters are optimized to achieve a uniform morphology of PLA nanofibers and PLA/nHAp composite fibers. The morphology and porosity of the fiber coatings were investigated by scanning electron microscopy. FTIR spectroscopy confirms the successful incorporation of nHAp into the PLA fibers, while electrochemical impedance spectroscopy demonstrates a significant improvement in corrosion resistance for the nanocomposite-coated titanium. Results show that the PLA/nHAp composite coatings prepared by electrospinning have promising features for applications in orthopedic and dental implantology.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.


