Electrospun nanofibrous coatings based on poly(lactic acid) (PLA) and bioactive nano-hydroxyapatite (nHAp) are developed to enhance the biocompatibility and corrosion resistance of titanium implants for medical applications. The electrospinning process parameters are optimized to achieve a uniform morphology of PLA nanofibers and PLA/nHAp composite fibers. The morphology and porosity of the fiber coatings were investigated by scanning electron microscopy. FTIR spectroscopy confirms the successful incorporation of nHAp into the PLA fibers, while electrochemical impedance spectroscopy demonstrates a significant improvement in corrosion resistance for the nanocomposite-coated titanium. Results show that the PLA/nHAp composite coatings prepared by electrospinning have promising features for applications in orthopedic and dental implantology.

Nanofibrous Coatings of Poly(Lactic Acid) and Nano‐Hydroxyapatite for Enhanced Biocompatibility of Titanium Implants / Ciarleglio, Gianluca; Pagani, Letizia; Ferri, Lorenzo; Toto, Elisa; Santonicola, Maria Gabriella. - In: MACROMOLECULAR SYMPOSIA. - ISSN 1022-1360. - (2025), pp. 1-3. [10.1002/masy.70248]

Nanofibrous Coatings of Poly(Lactic Acid) and Nano‐Hydroxyapatite for Enhanced Biocompatibility of Titanium Implants

Ciarleglio, Gianluca
Primo
;
Pagani, Letizia;Ferri, Lorenzo;Toto, Elisa;Santonicola, Maria Gabriella
Ultimo
2025

Abstract

Electrospun nanofibrous coatings based on poly(lactic acid) (PLA) and bioactive nano-hydroxyapatite (nHAp) are developed to enhance the biocompatibility and corrosion resistance of titanium implants for medical applications. The electrospinning process parameters are optimized to achieve a uniform morphology of PLA nanofibers and PLA/nHAp composite fibers. The morphology and porosity of the fiber coatings were investigated by scanning electron microscopy. FTIR spectroscopy confirms the successful incorporation of nHAp into the PLA fibers, while electrochemical impedance spectroscopy demonstrates a significant improvement in corrosion resistance for the nanocomposite-coated titanium. Results show that the PLA/nHAp composite coatings prepared by electrospinning have promising features for applications in orthopedic and dental implantology.
2025
coating; electrospinning; nanocomposite fiber; nano-hydroxyapatite; polylactic acid
01 Pubblicazione su rivista::01a Articolo in rivista
Nanofibrous Coatings of Poly(Lactic Acid) and Nano‐Hydroxyapatite for Enhanced Biocompatibility of Titanium Implants / Ciarleglio, Gianluca; Pagani, Letizia; Ferri, Lorenzo; Toto, Elisa; Santonicola, Maria Gabriella. - In: MACROMOLECULAR SYMPOSIA. - ISSN 1022-1360. - (2025), pp. 1-3. [10.1002/masy.70248]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1755557
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact