Background/Objectives: This study aims to evaluate and compare the diagnostic accuracy of skin lesion classification among three different classifiers: AI-based image classification, an expert dermatologist, and a non-expert. Given the rising interest in artificial intelligence (AI) within dermatology, it is crucial to assess its performance against human expertise to determine its viability as a reliable diagnostic tool. Methods: This reader study utilized a set of pre-labeled skin lesion images, which were assessed by an AI-based image classification system, an expert dermatologist, and a non-expert. The accuracy of each classifier was measured and compared against the ground truth labels. Statistical analysis was conducted to compare the diagnostic accuracy of the three classifiers. Results: The AI-based image classification system exhibited high sensitivity (93.59%) and specificity (70.42%) in identifying malignant lesions. The AI model demonstrated similar sensitivity and notably higher specificity compared to the expert dermatologist and non-expert. However, both the expert and non-expert provided valuable diagnostic insights, especially in classifying specific cases like melanoma. The results indicate that AI has the potential to assist dermatologists by providing a second opinion and enhancing diagnostic accuracy. Conclusions: This study concludes that AI-based image classification systems may serve as a valuable tool in dermatological diagnostics, potentially augmenting the capabilities of dermatologists. However, it is not yet a replacement for expert clinical judgment. Continued improvements and validation in diverse clinical settings are necessary before widespread implementation.

A comparison of skin lesions' diagnoses between ai-based image classification, an expert dermatologist, and a non-expert / Mevorach, Lior; Farcomeni, Alessio; Pellacani, Giovanni; Cantisani, Carmen. - In: DIAGNOSTICS. - ISSN 2075-4418. - 15:9(2025). [10.3390/diagnostics15091115]

A comparison of skin lesions' diagnoses between ai-based image classification, an expert dermatologist, and a non-expert

Farcomeni, Alessio;Pellacani, Giovanni;Cantisani, Carmen
2025

Abstract

Background/Objectives: This study aims to evaluate and compare the diagnostic accuracy of skin lesion classification among three different classifiers: AI-based image classification, an expert dermatologist, and a non-expert. Given the rising interest in artificial intelligence (AI) within dermatology, it is crucial to assess its performance against human expertise to determine its viability as a reliable diagnostic tool. Methods: This reader study utilized a set of pre-labeled skin lesion images, which were assessed by an AI-based image classification system, an expert dermatologist, and a non-expert. The accuracy of each classifier was measured and compared against the ground truth labels. Statistical analysis was conducted to compare the diagnostic accuracy of the three classifiers. Results: The AI-based image classification system exhibited high sensitivity (93.59%) and specificity (70.42%) in identifying malignant lesions. The AI model demonstrated similar sensitivity and notably higher specificity compared to the expert dermatologist and non-expert. However, both the expert and non-expert provided valuable diagnostic insights, especially in classifying specific cases like melanoma. The results indicate that AI has the potential to assist dermatologists by providing a second opinion and enhancing diagnostic accuracy. Conclusions: This study concludes that AI-based image classification systems may serve as a valuable tool in dermatological diagnostics, potentially augmenting the capabilities of dermatologists. However, it is not yet a replacement for expert clinical judgment. Continued improvements and validation in diverse clinical settings are necessary before widespread implementation.
2025
AI-based classification; dermatology; diagnostic accuracy; image recognition; machine learning; skin lesions
01 Pubblicazione su rivista::01a Articolo in rivista
A comparison of skin lesions' diagnoses between ai-based image classification, an expert dermatologist, and a non-expert / Mevorach, Lior; Farcomeni, Alessio; Pellacani, Giovanni; Cantisani, Carmen. - In: DIAGNOSTICS. - ISSN 2075-4418. - 15:9(2025). [10.3390/diagnostics15091115]
File allegati a questo prodotto
File Dimensione Formato  
Mevorach_Comparison_2025.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 703.84 kB
Formato Adobe PDF
703.84 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1743089
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact