The broad family of viruses known as anelloviruses (AV) infects both humans and numerous animal species. They have a tiny, covalently closed single-stranded DNA genome and the astonishing capacity to infect a very high percentage of healthy and ill people with chronic infections that could last a lifetime. AV, and particularly the prototype Torquetenovirus, have established a successful interaction with the host's immune system and the rate at which they replicate is a gauge to measure overall immune function, even though many aspects of their life cycle and pathogenesis are still poorly understood.
TTV and other anelloviruses: the astonishingly wide spread of a viral infection / Spezia, Pg; Focosi, D; Baj, A; Novazzi, F; Ferrante, Fd; Carletti, F; Minosse, C; Matusali, G; Maggi, F.. - In: ASPECTS OF MOLECULAR MEDICINE. - ISSN 2949-6888. - 1:(2023). [10.1016/j.amolm.2023.100006]
TTV and other anelloviruses: the astonishingly wide spread of a viral infection
Matusali GPenultimo
;
2023
Abstract
The broad family of viruses known as anelloviruses (AV) infects both humans and numerous animal species. They have a tiny, covalently closed single-stranded DNA genome and the astonishing capacity to infect a very high percentage of healthy and ill people with chronic infections that could last a lifetime. AV, and particularly the prototype Torquetenovirus, have established a successful interaction with the host's immune system and the rate at which they replicate is a gauge to measure overall immune function, even though many aspects of their life cycle and pathogenesis are still poorly understood.| File | Dimensione | Formato | |
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