Anti‑PD1 therapy in metastatic melanoma patients is associated with a high rate of cutaneous adverse events (AEs).[1] Atopic dermatitis (AD) is one of the AEs reported during therapy with pembrolizumab. Treatment of AD in cancer patients is challenging due to the limited availability of drugs. Dupilumab is a monoclonal antibody blocking IL‑4 and IL‑13 signalling.[2] Long‑term treatment with dupilumab in patients with moderate‑to‑severe AD has been shown to be safe and effective.
Atopic dermatitis onset in a Melanoma patient under Pembrolizumab therapy: a case of successful treatment with dupilumab / Tolino, Ersilia; Proietti, Ilaria; Skroza, Nevena; Guardo, Antonio Di; Fraia, Marco Di; Dybala, Agnieszka; Potenza, Concetta. - In: INDIAN JOURNAL OF DERMATOLOGY. - ISSN 0019-5154. - 69:3(2024), pp. 268-269. [10.4103/ijd.ijd_123_23]
Atopic dermatitis onset in a Melanoma patient under Pembrolizumab therapy: a case of successful treatment with dupilumab
Tolino, Ersilia;Proietti, Ilaria;Skroza, Nevena;Guardo, Antonio Di;Fraia, Marco Di
;Dybala, Agnieszka;Potenza, Concetta
2024
Abstract
Anti‑PD1 therapy in metastatic melanoma patients is associated with a high rate of cutaneous adverse events (AEs).[1] Atopic dermatitis (AD) is one of the AEs reported during therapy with pembrolizumab. Treatment of AD in cancer patients is challenging due to the limited availability of drugs. Dupilumab is a monoclonal antibody blocking IL‑4 and IL‑13 signalling.[2] Long‑term treatment with dupilumab in patients with moderate‑to‑severe AD has been shown to be safe and effective.| File | Dimensione | Formato | |
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